Structural organization of membrane-inserted hexamers formed byHelicobacter pyloriVacA toxin

Probing Pores with Peptide Plugs: Topology of Membrane-inserted Diphtheria Toxin

Extracellular proteins are made in the cytosol and transported out of the cell. Certain proteins travel the opposite way, from the outside to the cytosol. Most of these proteins are toxins made by bacteria and plants, but evidence is accumulating that certain growth factors can do the same. Toxins that enter the cytosol can, according to current knowledge, be roughly classified into two main gr...

Conformation of membrane-inserted P-glycoprotein

Background The human genome codes for 49 members of the large ABC protein family. Most of them are membrane transporters. The first structures of exporters have been solved in recent years. Although a remarkable achievement, some uncertainty remained with respect to the physiological conformation of the transporter, which seems not to be fully compatible with all biochemical evidence. During cr...

MMP 14 ( matrix metallopeptidase 14 ( membrane - inserted ) )

Immune response to cholera toxin epitope inserted in Salmonella flagellin.

Bacterial flagella are potent immunogens and aromatic-dependent (aro) Salmonella as live vaccines evoke humoral and cellular immune responses. Such strains expressing epitopes of protective antigens as inserts in flagellin would provide a novel way to vaccinate against diseases caused by unrelated pathogens. A synthetic oligonucleotide specifying an epitope of cholera toxin subunit B was insert...

a structural survey of the polish posters

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